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Project # 11
Development of a novel 3D model to investigate prong-induced nasal septal septum injury in preterm infants

Team Lead: Rowa Hamdan
Other Team Members: Le Hoang
Faculty Advisor(s): Dr. Liping Tang and Dr. Shiyao Lin
Department: BE
Project Type: Graduate Student
Title: Development of a novel 3D model to investigate prong-induced nasal septal septum injury in preterm infants
Abstract: Premature neonates, defined as infants born before 37 weeks of gestational age, often face respiratory difficulties due to underdeveloped tracts. Continuous positive airway pressure (CPAP) is a standard non-invasive ventilation method for these infants, yet it can cause nasal deformities, including columella erosion. Approximately 20-60% of preterm infants experience such injuries, which result from the pressure exerted by nasal prongs, a necessary component of CPAP. The risk is higher in infants with weaker skin and prolonged ventilation needs. Current guidelines recommend frequent monitoring and alternating between nasal prongs and masks to reduce injury. However, studies show a lack of comprehensive tools assessing the risk of nasal injuries. This research aims to investigate the impact of nasal prongs on preterm infants' nasal structures, hypothesizing that their narrower, softer nasal canals increase susceptibility to pressure injuries. Using 3D models derived from MRI scans of neonatal faces and CPAP prongs, we will simulate the stress-strain interactions to understand how prongs cause damage. This study will provide critical insights into the mechanical forces at play, with the goal of reducing CPAP-related injuries and improving neonatal care. By combining virtual modeling and simulation, we hope to develop more effective solutions for this persistent issue.
Poster: View Poster #11 (PDF)
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