| Abstract: | Peripheral arterial disease (PAD) is the pathological condition when the blood flow to the lower extremities is limited due to the blockage of the blood vessels, which leads to a high rate of morbidity and mortality. Over 8.5 million Americans have been affected with PAD, the majority of whom are elderly. The common approach to treat PAD includes invasive surgical intervention, which can cause discomfort in patients and post-surgical complications, and is not an effective option for elderly patients. Therefore, our goal is developing a less-invasive approach to treat PAD using EpoR loaded nanoparticles made of the imaging enabled BPLPAT. |