| Abstract: | Human stem cells are special types of cells that have a high ability to develop into different cell types. The stem cells can be developed and used to replace damaged organs and tissues. Stem cells are medically used to treat serious illnesses and diseases. At a high demand, the stem cell production process is done at a low rate because the stem cells are sensitive and easy to differentiate into undesired forms of cells. In a traditional method, stem cells are grown and incubated on solid (sphere) surfaces in a controlled and sterile environment. The cells grown on surfaces require circulation and agitation to maintain a uniform level of oxygen and food in the cell culture media, which can be damaged by a process shear force. This research is focusing on improving the stem cell harvesting method by growing the cells inside hollow microcarriers (HMCs) to avoid cell differential from the shear force, and the automation system will be integrated to enhance the process. |